Born: 28.03.1989, Oleśnica

Hobby: sewing, sport

e-mail: karolina.swiderska@pwr.edu.pl

Phone: (+48) 71 320 24 55

Education

MSc in Chemistry, 2013, University of Wroclaw, Poland, Chemistry and Stereochemistry of Peptides and Protein, “Cyclic peptides containingHis residues as ligands for metal ions - synthesis and MS studies” supervisor: PhD Marek Cebrat

PhD in Biotechnology, 2018, University of Wroclaw, Poland, Protein Engineering, "Basic fibroblast growth factor (FGF2) conjugatecontaining two cytotoxic warhead with different mechanism of action" supervisor: PhD, DSc, Jacek Otlewski

Publications

1. Świderska KW, Szlachcic A, Opaliński Ł, Zakrzewska M, Otlewski J, FGF2 Dual Warhead Conjugate with Monomethyl Auristatin E and a-Amanitin Displays a Cytotoxic Effect towards Cancer Cells Overproducing FGF Receptor 1 International Journal of Molecular Sciences 2018, 19, 2098. View at Publisher
2. Swiderska KW, Szlachcic A, Czyrek A, Zakrzewska M, Otlewski J, Site-specific conjugation of fibroblast growth factor 2 (FGF2) based on incorporation of alkyne-reactive unnatural amino acid. Bioorganic & Medicinal Chemistry 2017, 25, 3685. View at Publisher
3. Krzyscik M; Zakrzewska M; Sorensen V; Sokolowska-Wedzina A; Lobocki M; Swiderska KW; Krowarsch D.; Wiedlocha A.; Otlewski J., Cytotoxic Conjugates of Fibroblast Growth Factor 2 (FGF2) with Monomethyl Auristatin E for Effective Killing of Cells Expressing FGF Receptors ACS Omega 2017, 2, 3792. View at Publisher
4. Sochaj AM, Świderska KW, Otlewski J, Current methods for the synthesis of homogeneous antibody-drug conjugates Biotechnology Advances 2015, 33, 775. View at Publisher