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Department of Chemical Biology and Bioimaging

Natalia Małek Ph.D.

natalia2.jpg

Born: 20.04.1986

Hobby: travel, escape rooms

e-mail: natalia.malek@pwr.wroc.pl

Phone: (+48) 71 320 2455

Google scholar profile (https://scholar.google.com/citations?user=UjkMAQsAAAAJ&hl=en)

Education

Ph.D., 2013-2017 Polish Academy of Sciences, Institute of Pharmacology, Department of Pain, Pharmacology; field: medical sciences, neuropsychopharmacology

M.Sc., 2008-2015 Jagiellonian University, Collegium Medicum, Faculty of Pharmacy, major: Pharmacy

M.Sc., 2005-2010 Jagiellonian University, Faculty of Biochemistry, Biophysics and Biotechnology, major: Biotechnology

Former positions

2017 – 2019 University of Wroclaw, Faculty of Biotechnology, post-doc position in the NCN project

2011 – 2013 Polish Academy of Sciences, Institute of Pharmacology, Department of Pain Pharmacology, assistant position in the LIDER project

Research stays

2017 University of Bonn, CEASAR, Department of Structural Biology, short-term internship in the framework of START FNP program

2016 King's College London, Wolfson's Center of Age-Related Diseases, internship under ETIUDA NCN program

2012 Hungarian Academy of Sciences, Biological Research Center. Short stay as a part of International scientific cooperation on "Role of the endocannabinoid system in neuropathic pain."

2009 – 2010 University of Helsinki, Faculty of Medicine, Genome-Scale Biology Program, Viral Tumorgenesis Group, internship under the ERASMUS program

Awards and honours

2018 September, Scholarship for outstanding young scientists by Ministry of Science and Higher Education Poland

2018 November, Nomination to Academy of Young Scientists and Artists in Wroclaw

2017 May, Scholarship for promising young scientists of the Foundation for Polish Science START

2016 December, Award of the President of the Polish Academy of Sciences for the outstanding scientific achievements of PhD students

2016 July, The prize for the best oral presentation at the 26th Congress of the International Cannabinoid Research Society

2015 November, Scholarship for the best PhD students. Institute of Pharmacology, Polish Academy of Sciences

2015 September, ETIUDA project granted by National Science Centre

2015 October, PhD scholarship of the L'Oreal Foundation "For women and science", with the UNESCO Committee and the Ministry of Science and Higher Education

2015 August, Roche award for participation in "Roche Continents 2015"

2015 June, Nomination for a student representative on the Board of Directors the International Cannabinoid Research Society for 2015-2017

2013 June, FENS / IBRO scholarship: European Pain School "Brain modulation of pain experience"

2013 May, "Diamond grant" project awarded by the Ministry of Science and Higher Education

2013 November, Scholarship for the best PhD students. Institute of Pharmacology, Polish Academy of Sciences

Publications (from ISI Master Journal List)

  1. Malek N, Starowicz K., Joint problems arising from lack of repair mechanisms: can cannabinoids help? British Journal of Pharmacology 2018, 1. View at Publisher
  2. Korostynski M, Malek N, Piechota M, Starowicz K., Cell-type-specific gene expression patterns in the knee cartilage in an osteoarthritis rat model Functional & Integrative Genomics 2018, 18, 79. View at Publisher
  3. Mlost J, Kostrzewa M, Malek N, Starowicz K, Molecular Understanding of the Activation of CB1 and Blockade of TRPV1 Receptors: Implications for Novel Treatment Strategies in Osteoarthritis International Journal of Molecular Sciences 2018, 19, 342. View at Publisher
  4. Lopes DM*, Malek N*, Edye M, Jager SB, McMurray S, McMahon SB, Denk F (*equal contribution), Sex differences in peripheral not central immune responses to pain-inducing injury Scientific Reports 2017, 7, 16460. View at Publisher
  5. Pajak A, Kostrzewa M, Malek N, Korostynski M, Starowicz K, “Expression of matrix metalloproteinases and components of the endocannabinoid system in the knee joint are associated with biphasic pain progression in a rat model of osteoarthritis Journal of Pain Research 2017, 1973. View at Publisher
  6. Korostyński M, Malek N, Piechota M, Starowicz K, Blood Transcriptional Signatures for Disease Progression in a Rat Model of Osteoarthritis International Journal of Genomics 2017, 1746426. View at Publisher
  7. Malek N, Starowicz K, Dual-Acting Compounds Targeting Endocannabinoid and Endovanilloid Systems—A Novel Treatment Option for Chronic Pain Management Frontiers in Pharmacology 2016, 7, 257. View at Publisher
  8. Malek N, Kostrzewa M, Makuch W, Pajak A, Kucharczyk M, Piscitelli F, Przewlocka B, Di Marzo V, Starowicz K, The multiplicity of spinal AA-5-HT anti-nociceptive action in a rat model of neuropathic pain Pharmacological Research 2016, 111, 251. View at Publisher
  9. Malek N, Popiolek-Barczyk K, Mika J, Przewlocka B, Starowicz K, Anandamide, acting via CB2 receptors, alleviates LPS-induced neuroinflammation in rat primary microglial cultures Neural Plasticity 2015, 130639. View at Publisher
  10. Mika J, Jurga A, Starnowska J, Wasylewski M, Rojewska E, Makuch W, Malek N, Przewlocka B, Effects of chronic doxepin and amitriptyline administration in naive mice and in neuropathic pain mice model Neuroscience 2015, 294, 38. View at Publisher
  11. Malek N, Mrugala M, Makuch W, Kolosowska N, Przewlocka B, Binkowski M, Czaja M, Morera E, Di Marzo V, Starowicz K, A multi-target approach for pain treatment - dual inhibition of fatty acid amide hydrolase and TRPV1 in a rat model of osteoarthritis Pain 2015, 156, 890. View at Publisher
  12. Malek N, Pajak A, Kolosowska N, Kucharczyk M, Starowicz K, The importance of TRPV1-sensitisation factors for the development of neuropathic pain Molecular and cellular neurosciences 2015, 65, 1. View at Publisher
  13. Malek N, Kucharczyk M, Starowicz K, Alterations in the anandamide metabolism in the development of neuropathic pain BioMed Research International 2014, 686908. View at Publisher
  14. Starowicz K, Makuch W, Korostynski M , Malek N, Slezak M, Zychowska M, Petrosino S, De Petrocellis L, Cristino L, Przewlocka B, Di Marzo V., Full inhibition of spinal FAAH leads to TRPV1-mediated analgesic effects in neuropathic rats and possible lipoxygenase-mediated remodeling of anandamide metabolism PLoS One 2013, 8, 60040. View at Publisher
  15. Golda A, Malek N, Dudek B, Zeglen S, Wojarski J, Ochman M, Kucewicz E, Zembala M, Potempa J, Pyrc K, Infection with human coronavirus NL63 enhances streptococcal adherence to epithelial cells The Journal of General Virology 2011, 92, 1358. View at Publisher
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