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Department of Chemical Biology and Bioimaging

2015

Studnik, H.; Liebsch, S.; Forlani, G.; Wieczorek, D.; Kafarski, P.; Lipok, J., Amino polyphosphonates – chemical features and practical uses, environmental durability and biodegradation New Biotechnol. 2015, 32, 1.

Macegoniuk, K.; Dziełak, A.; Mucha, A.; Berlicki, Ł., Bis(aminomethyl)phosphinic acid, a highly promising scaffold for the development of bacterial urease inhibitors. ACS Med. Chem. Lett. 2015, 6, 146.

Hachmann, J.; Edgington-Mitchell, L. E.; Poreba, M.; Sanman, L. E.; Drag, M.; Bogyo, M.; Salvesen, G. S., Probes to Monitor Activity of the Paracaspase MALT1 Chem. Biol. 2015, 22, 139.

Lechtenberg, B. C.; Kasperkiewicz, P.; Robinson, H.; Drag, M.; Riedl, S. J., The Elastase-PK101 structure: Mechanism of an ultrasensitive activity-based probe revealed ACS Chem. Biol. 2015, 10, 945.

Rut, W.; Kasperkiewicz, P.; Byzia, A.; Poreba, M.; Groborz, K.; Drag, M., Recent advances and concepts in substrate specificity determination of proteases using tailored libraries of fluorogenic substrates with unnatural amino acids Biol. Chem. 2015, 396, 329.

Arya, T.; Reddi, R.; Kishor, C.; Ganji, R.J.; Bhukya, S.; Gumpena, R.; McGowan, S.; Drag, M.; Addlagatta, A., Identification of the molecular basis of inhibitor selectivity between the human and Streptococcal Type I methionine aminopeptidases. J. Med. Chem. 2015, 58, 2350.

Lenartowicz, P.; Kafarski, P.; Lipok, J., The overproduction of 2,4-DTBP accompanying to the lack of available form of phosphorus during the biodegradative utilization of aminophosphonates by Aspergillus terreus Biodegradation 2015, 26, 65.

Zymanczyk-Duda, E.; Brzezinska-Rodak, M.; Kozyra, K.; Klimek-Ochab, M., Fungal Platform for Direct Chiral Phosphonic Building Blocks Production. Closer Look on Conversion Pathway Appl. Biochem. Biotechnol. 2015, 175, 1403.

Hachmann J, Edgington-Mitchell LE, Poreba M, Sanman LE, Drag M, Bogyo M, Salvesen GS., Probes to monitor activity of the paracaspase MALT1 Chemistry & biology 2015, 22, 139.

Bekes, M.; Rut, W.; Kasperkiewicz, P. Mulder, M. P.; Ovaa, H.; Drag, M.; Lima, C. D.; Huang, T. T., SARS hCoV papain-like protease is a unique Lys48 linkage-specific di-distributive deubiquitinating enzyme. Biochem. J. 2015, 468, 215.

Oszywa, B.; Pawełczak, M.; Kafarski, P, The influence of alpha-aminophosphonic acids on the activity of aminopeptidase from barley seeds—an approach to determine the enzyme specificity Acta Physiol. Plant. 2015, 37, 1.

Chmielewska, E.; Miszczyk, P.; Kozłowska, J.; Prokopowicz, M.; Młynarz, P.; Kafarski. P., Reaction of benzolactams with triethyl phosphite prompted by phosphoryl chloride affords benzoannulated monophosphonates instead of expected bisphoshonates J. Organomet. Chem. 2015, 785, 84.

Kiełbowicz, Z.; Piątek, A.; Bieżyński, J.; Skrzypczak, P.; Chmielewska, E. Kafarski, P.; Kuryszko, J., Improvement of large animal model for studying osteoporosis Bull. Vet. Inst. Pulawy 2015, 59, 123.

Kafarski, P.; Lipok, M., Chapter 11. Structural analogy - direct similarity versus topographical complementarity book: Drug Discovery and Development - From Molecules to Medicine 2015, 2015, 241.

Waclawczyk-Biedron, W., Frackowiak-Wojtasek, B., Strub, D., Rzechak, M., Wojtasek, H., Synthesis of the aggregation pheromone of the Colorado potato beetle from its degradation product Bioorg. Med. Chem. Lett. 2015, 17, 3560.

Dobosz, A.; Spychała, J.; Ptak, T.; Maciejewska, G.; Chmielewska, E.; Kafarski, P.; Młynarz, P., Interactions of N-heteroalkylaminomethylenebisphosphonic acids with Cd(II) ions: Electrochemical and spectroscopic investigations Inorg. Chim. Acta 2015, 435, 82.

Dziełak, A.; Mucha, A., Catalytic and MW-Assisted Michaelis-Arbuzov Reactions Curr. Green Chem. 2015, 2, 223.

Kafarski, P.; Górny vel Górniak, M.; Andrasiak, I., Kabachnik-Fields Reaction Under Green Conditions – A Critical Overview Curr. Green Chem. 2015, 2, 218.

Drag-Zalesinska M, Wysocka T, Borska S, Drag M, Poreba M, Choromanska A, Kulbacka J, Saczko J., The new esters derivatives of betulin and betulinic acid in epidermoid squamous carcinoma treatment - In vitro studies. Biomedicine & Pharmacotherapy 2015, 72, 91.

Kasperkiewicz P, Poreba M, Snipas SJ, Lin SJ, Kirchhofer D, Salvesen GS, Drag M., Design of a Selective Substrate and Activity Based Probe for Human Neutrophil Serine Protease 4. PLoS One 2015, 10, 1.

Maciejczyk, E.; Wieczorek, D.; Zwyrzykowska, A.; Halama, M.; Jasicka-Misiak, I., Kafarski, P., Phosphorus profile of Basidomycetes Phosphorus, Sulfur, Silicon Relat. Elem. 2015, 190, 763.

Kuźnik, A.; Mazurkiewicz, R.; Grymel, M.; Zielińska, K.; Adamek, J.; Chmielewska, E. Bochno, M.; Kubica, S., A new method for the synthesis of ?-aminoalkylidenebisphosphonates and their asymmetric phosphonyl-phosphinyl and phosphonyl-phosphinoyl analogues Beilstein J. Org. Chem. 2015, 11, 1418.

Rudzińska-Szostak, E.; Górecki, Ł. Berlicki, Ł.; Ślepokura, K.; Mucha, A., Zwitterionic Phosphorylated Quinines as Chiral Solvating Agents for NMR Spectroscopy Chirality 2015, 27, 752.

Makowski, M.; Lenartowicz, :P.; Oszywa, B.; Jewgiński, M.; Pawełczak, M.; Kafarski, P., Synthesis of dehydrodipeptide esters and their evaluation as inhibitors of cathepsin C Med. Chem. Res. 2015, 24, 3157.

Majewska P., Biotransformations of 2-hydroxy-2-(ethoxyphenylphosphinyl)acetic acid and the determination of the absolute configuration of all isomers. Bioorg. Chem. 2015, 61, 28.

Rajkovic, J.; Poreba, M.; Caglic, D.; Vidmar, R.; Wilk, A.; Borowik, A.; Salvesen, G. S.; Turk, V.; Drag, M.; Turk, B., Biochemical Characterization and Substrate Specificity of Autophagin-2 from the Parasite Trypanosoma cruzi J. Biol. Chem. 2015, 290, 28231.

Górak, M.; Żymańczyk-Duda, E., Application of cyanobacteria for chiral phosphonate synthesis. Green Chem. 2015, 17, 4570.

Galiullina RA, Kasperkiewicz P, Chichkova NV, Szalek A, Serebryakova MV, Poreba M, Drag M, Vartapetian AB, Substrate Specificity and Possible Heterologous Targets of Phytaspase, a Plant Cell Death Protease. Journal of Biological Chemistry 2015, 290, 24806.

Poreba M, Szalek A, Kasperkiewicz P, Rut W, Salvesen GS, Drag M, Small Molecule Active Site Directed Tools for Studying Human Caspases Chemical Reviews 2015, 115, 12546.

Byzia A, Szeffler A, Kalinowski L, Drag M, Activity profiling of aminopeptidases in cell lysates using a fluorogenic substrate library. Biochimie 2015, 15, 00310.

van der Linden WA, Segal E, Child MA, Byzia A, Drąg M, Bogyo M., Design and Synthesis of Activity-Based Probes and Inhibitors for Bleomycin Hydrolase. Chem Biol 2015, 22, 995.

Kiełbowicz, Z.; Piątek, A.; Bieżyński, J.; Skrzypczak, P.; Kuropka, P.; Kuryszko, J.; Nikodem, A.; Kafarski, P.; Cezowicz, P., The Experimental Osteoporosis in Sheep – Clinical Approach Pol. J. Veterinary Sci. 2015, 18, 645.

Chmielewska, E.; Mazur, Z.; Kempińska, K.; Wietrzyk, J.; Piątek, A.; Kuryszko, J. J.; Kiełbowicz, Z; Kafarski P., N-Arylaminomethylenebisphosphonates Bearing Fluorine Atoms: synthesis and Antiosteoporotic Activity Phosphorus, Sulfur, Silicon Relat. Elem 2015, 190, 2164.

Zabek, A; Stanimirova, I; Deja, S; Barg, W; Kowal, A; Korzeniewska, A; Orczyk-Pawilowicz, M; Baranowski, D; Gdaniec, Z; Jankowska, R; Mlynarz, P, Fusion of the H-1 NMR data of serum, urine and exhaled breath condensate in order to discriminate chronic obstructive pulmonary disease and obstructive sleep apnea syndrome METABOLOMICS 2015, 11, 1563.

Zabek, A.; Nagaj, J.; Grabowiecka, A.; Dworniczek, E.; Nawrot, U.; Młynarz, P.; Jeżowska-Bojczuk, M., Activity of fluconazole and its Cu(II) complex towards Candida species Med. Chem. Res. 2015, 24, 2005.

Jawień, E.; Ząbek, A.; Deja S.; Łukaszewicz, M.; Młynarz, P., 1H NMR-based metabolic profiling for evaluating poppy seed rancidity and brewing Chem. Mol. Biol. Lett. 2015, 20, 752.

van der Linden, W. A.; Segal, E.; Child, M. A.; Byzia, A. Drąg, M.; Bogyo, M., Design and Synthesis of Activity-Based Probes and Inhibitors for Bleomycin Hydrolase Chem. Biol. 2015, 22, 995.

Kaczmarczyk, D., Strub, D., Polowy, A., Wilk, K.A., Lochyński, S., Selected Essential Oils in Cosmetic Emulsions: Process Oriented Stability Studies and Antimicrobial Activity Nat. Volatiles & Essent. Oils 2015, 2, 27.

Kaczmarczyk, D., Lochyński, S., Microorganisms present in products of biotransformation of tea. Pol. J. Cosmetol. 2015, 18, 241.

Kaczmarczyk D., Lochyński S., Kombucha broth as a natural source of organic acids Na pograniczu chemii i biologii, Wydawnictwo Naukowe UAM, Poznań 2015, 35, 13.

Stryjewska, A., Lochyński, S., Biosynthesis of two new derivatives with a fenchane unit, obtained by biotransformation with Aspergillus niger ATCC 10549 PhD Interdysciplinary Journal 2015, 1, 133.

Szmigiel, B.; Żymańczyk-Duda, E.; Lochyński, S., Procedura zabiegowa eksfoliacji z zastosowaniem hydroksykwasów. Pol. J. Cosmet. 2015, 18, 119.

Górak, M.; Serafin, M.; Klimek-Ochab, M.; Żymańczyk-Duda, E., Bioocatalitic transformation of epoxy- and vinylphosphonates Chemik 2015, 69, 273.

Górak M, Serafin M, Klimek-Ochab M, Żymańczyk-Duda E, Biocatalytic transformation of epoxy- and vinylphosphonates Chemik 2015, 69, 273.

Siwak, E., Jewgiński, M., Kustrzeba-Wójcicka, I., Biological activity of surfactins - A case of a biosurfactant produced by Bacillus subtilis PCM 1949 Acta Biochimica Polonica 2015, 62, 875.

Makowski, M., Lenartowicz, P., Oszywa, B., Jewgiński, M., Pawełczak, M., Kafarski, P., Synthesis of dehydrodipeptide esters and their evaluation as inhibitors of cathepsin C Medicinal Chemistry Research 2015, 24, 3157.

Góra, J.; Latajka, R., Involvement of Cysteine Proteases in Cancer. Curr. Med. Chem. 2015, 22, 944.

Sochaj AM, Świderska KW, Otlewski J, Current methods for the synthesis of homogeneous antibody-drug conjugates Biotechnology Advances 2015, 33, 775.

Malek N, Popiolek-Barczyk K, Mika J, Przewlocka B, Starowicz K, Anandamide, acting via CB2 receptors, alleviates LPS-induced neuroinflammation in rat primary microglial cultures Neural Plasticity 2015, 130639.

Mika J, Jurga A, Starnowska J, Wasylewski M, Rojewska E, Makuch W, Malek N, Przewlocka B, Effects of chronic doxepin and amitriptyline administration in naive mice and in neuropathic pain mice model Neuroscience 2015, 294, 38.

Malek N, Mrugala M, Makuch W, Kolosowska N, Przewlocka B, Binkowski M, Czaja M, Morera E, Di Marzo V, Starowicz K, A multi-target approach for pain treatment - dual inhibition of fatty acid amide hydrolase and TRPV1 in a rat model of osteoarthritis Pain 2015, 156, 890.

Malek N, Pajak A, Kolosowska N, Kucharczyk M, Starowicz K, The importance of TRPV1-sensitisation factors for the development of neuropathic pain Molecular and cellular neurosciences 2015, 65, 1.

Kowalczyk, R.; Wierzba, A.J.; Boratyński, P.J.; Bąkowicz, J., Site and stereoselectivity in sulfa-Michael addition to equivocally activated conjugated dienes RSC Advances 2015, 5, 66681.

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